The liver is a football-sized organ sitting under the right part of the abdomen. It participates in the detoxification, digestion, and transportation of enzymes and hormones.<\/p>\n
\nCommon liver diseases include hepatitis, fibrosis, cirrhosis, and cancer. Liver problems can be caused by multiple factors, such as alcohol abuse, viruses, or other medical conditions like obesity. Some liver diseases can be inherited\/genetic and can lead to further disease progression if not treated.<\/p>\n
\nNASH, or Non-Alcoholic Steatohepatitis, is a liver disease that attacks the liver cells and causes a build-up of fats. Over time, NASH can lead to cirrhosis and potentially liver failure, which is considered a life-threatening condition.<\/p>\n
\nIn this brief guide, we\u2019ll talk about the causes, symptoms, and diagnosis of NASH and whether people can prevent it from progressing. Read on to learn more about it.<\/p>\n
\nAccording to experts, the known causes of NASH are still under research. However, there\u2019s limited understanding that NAFLD and NASH develop under certain circumstances and are linked to type 2 diabetes, obesity, hyperglycemia, and high levels of fats.<\/p>\n
\nAll of these medical conditions combined can lead to the development of Non-Alcoholic Steatohepatitis, which causes a build-up of fats in the liver cells. For some people, the fat build-up in the liver can cause liver inflammation and act as a toxin to the liver cells, leading to scarring and fibrosis over time.<\/p>\n
\nThe risk of NASH is increased when the patient suffers from the following:<\/p>\n
High cholesterol<\/p>\n
PCOS – Polycystic Ovary Syndrome<\/p>\n
Sleep apnea<\/p>\n
Hypothyroidism – underactive thyroid<\/p>\n
Hypopituitarism – underactive pituitary gland<\/p>\n
Obesity<\/p>\n
Metabolic syndrome<\/p>\n
Oxidative stress – an imbalance between the antioxidants and the free radicals in the body<\/p>\n
Intestinal bacteria – causing liver inflammation<\/p>\n
Genetic diseases<\/p>\n
Apoptosis – programmed cell death<\/p>\n
Overproduction of cytokines<\/p>\n
Based on some statistics, NASH is more likely to develop in people with diabetes, older people, and those with most of their fat concentrated around the belly area and the abdomen. Also at increased risk are Hispanic or Asian people, women in the postmenopausal period, or people suffering from high blood pressure.<\/p>\n
\nMany tests are performed to diagnose NASH, including a NASH blood test, biopsies, and imaging methods. We\u2019ll discuss the diagnostic methods later in this article.<\/p>\n
\nThe early stages of NASH usually display no symptoms at all since it\u2019s a silent disease. Over time, the disease will progress, and the person might show symptoms of fatigue and pain or discomfort in the right part of the abdomen.<\/p>\n
\nAs the disease advances to its later stages, symptoms like abdominal swelling or ascites, enlarged spleen, red palms, enlarged blood vessels, and jaundice appear. Additional symptoms like behavioral changes, including confusion or slurred speech, intense itchiness, and easy bruising, can also be indicators of NASH.<\/p>\n
\nNon-alcoholic steatohepatitis makes it difficult for the liver to function, which leads to liver damage and swelling that can be serious or even life-threatening.<\/p>\n
\nMake an appointment with your doctor immediately if you have any of these symptoms persistently.<\/p>\n
\nLiver treatment<\/p>\n
\nCopyright: Julien Tromeur on Unsplash I License: CC0 Public Domain<\/p>\n
\nSince people with NASH don\u2019t usually experience any symptoms, it can be difficult to diagnose the disease in its early stages. Doctors usually recognize liver problems from other regular screenings or routine blood tests.<\/p>\n
\nHigh levels of certain enzymes in the blood show liver disease, damage, inflammation, or injury.<\/p>\n
\nSome common liver function tests are ALT (alanine aminotransferase) and AST (aspartate aminotransferase). These show liver inflammation and rule out other diseases.<\/p>\n
\nOther common tests are:<\/p>\n
Alkaline phosphatase – ALP<\/p>\n
Albumin and total protein tests<\/p>\n
Bilirubin test<\/p>\n
Gamma-glutamyltransferase test – GGT<\/p>\n
Prothrombin time<\/p>\n
\nImaging tests like MRI, ultrasound, and CT are used to get imaging of the internal organs, tissues, and structures and diagnose scarring, fibrosis, or tumors.<\/p>\n
\nThis is a minimally-invasive procedure that involves taking a small liver sample through a thin needle. The most common type of liver biopsy is percutaneous liver biopsy, where the liver tissue is taken through the belly.<\/p>\n
\nA liver biopsy is used when the healthcare provider needs to diagnose a liver problem, obtain a sample tissue from the liver and send it for a lab examination to rule out liver cancer, determine the stages of the disease and develop a treatment plan based on the liver\u2019s condition.<\/p>\n
\nThe healthcare provider might order a biopsy if there are irregular liver tests that can\u2019t be explained or other irregularities or tumors are seen on the imaging tests. A liver biopsy is commonly performed to diagnose:<\/p>\n
\n\u25cf Chronic hepatitis B<\/p>\n
\u25cf Chronic hepatitis C<\/p>\n
\u25cf Primary biliary cholangitis<\/p>\n
\u25cf Hemochromatosis<\/p>\n
\u25cf Autoimmune hepatitis<\/p>\n
\u25cf NAFLD and NASH<\/p>\n
\u25cf Liver cirrhosis<\/p>\n
\u25cf Wilson\u2019s disease<\/p>\n
\nIt\u2019s important to take care of your health and go for regular check-ups. Your healthcare provider will inform you of the further steps if liver disease is diagnosed, so make sure you stay healthy and listen to your doctor\u2019s advice.<\/p>\n","protected":false},"excerpt":{"rendered":"
The liver is a football-sized organ sitting under the right part of the abdomen. It participates in the detoxification, digestion, and transportation of enzymes and hormones. Common liver diseases include hepatitis, fibrosis, cirrhosis, and cancer. Liver problems can be caused by multiple factors, such as alcohol abuse, viruses, or other medical conditions like obesity. Some […]<\/p>\n","protected":false},"author":1,"featured_media":17029,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[77],"tags":[],"class_list":["post-17028","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health-care"],"acf":[],"_links":{"self":[{"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/posts\/17028","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/comments?post=17028"}],"version-history":[{"count":0,"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/posts\/17028\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/media\/17029"}],"wp:attachment":[{"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/media?parent=17028"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/categories?post=17028"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/sites5.dotoit.media\/primeold\/wp-json\/wp\/v2\/tags?post=17028"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}